Background of the target antigen:
Involved in redox regulation of the cell. Reduces peroxides with reducing equivalents provided through the thioredoxin system. It is not able to receive electrons from glutaredoxin. May play an important role in eliminating peroxides generated during metabolism. Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H(2)O(2).
Synonym names:
PRP; TSA; PRX2; PTX1; TPX1; NKEFB; PRXII; TDPX1; NKEF-B; HEL-S-2a; Peroxiredoxin-2; Natural killer cell-enhancing factor B; Thiol-specific antioxidant protein; Thioredoxin peroxidase 1; Thioredoxin-dependent peroxide reductase 1; PRDX2
Specificity:
This is a highly specific antibody against Peroxiredoxin 2. This antibody may have a minor secondary cross-reactivity to related protein Peroxiredoxin 1 due to a 71% non-sequential sequence similarity over the immunogen range.
Properties:
If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
Storage conditions:
Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
Source:
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Peroxiredoxin 2
Cross reactive species details:
Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
Recommended dilutions:
WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
Long name:
Peroxiredoxin 2 Primary Polyclonal Antibody
Purification method:
This antibody was purified via Protein A.
Tested Applications:
WB, IHC-P, IF(IHC-P)
Clone number:
Polyclonal antibody
Modification site(s):
Unmodified antibody
Clonality:
Polyclonal antibody
Also known as:
Peroxiredoxin 2 PAb
Category:
Primary Antibodies
Cross reactivity:
Human, Mouse, Rat
Target Antigen:
Peroxiredoxin 2
Conjugation:
Unconjugated
Concentration:
1ug per 1ul
Immunogen range:
150-197/198
Subcellular location:
Cytoplasm
French translation:
anticorps
Swiss Prot:
P32119
Gene ID number:
7001
Modification(s):
None