Background:
Peroxiredoxin 6 belongs to the thiol-specific antioxidant protein family, which is a bifunctional enzyme with two distinct active sites. Peroxiredoxin 6 is involved in redox regulation of the cell and can reduce Hydrogen peroxide and short chain organic, fatty acid, and phospholipid hydroperoxides. Peroxiredoxin 6 may regulates phospholipid turnover and protectes against oxidative injury. Peroxiredoxin 6 eases the oxidative stress and TGF-beta-induced abnormalities of human trabecular meshwork cells, it is necessary for blood vessel integrity in injured skin.
Properties:
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Synonym:
Peroxiredoxin-6; 1-Cys Peroxiredoxin; 1-Cys PRX; 24 kDa Protein; Acidic Calcium-Independent Phospholipase A2; aiPLA2; Antioxidant Protein 2; Liver 2D PAGE Spot 40; Non-Selenium Glutathione Peroxidase; NSGPx; Red Blood Cells Page Spot 12; PRDX6; AOP2; KIAA0106
Shipping:
The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.
Stability and Storage:
Store at < -20℃, stable for 6 monthshs after receipt.Please minimize freeze-thaw cycles
Formulation:
Supplied as a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2.
Endotoxin:
＜1.0 EU per µg as determined by LAL test.
Purity:
＞95% as determined by reducing SDS-PAGE.
Source:
Recombinants or rec. proteins
Group:
recombinants
Sequence:
Met1-Pro224
Mol Mass:
27.2 kDa
Expressed Host:
E.coli
AP Mol Mass:
30 kDa
Accession:
P30041
Fusion tag:
N-6His
Activity:
NA