Background of the target antigen:
Involved in redox regulation of the cell. Reduces peroxides with reducing equivalents provided through the thioredoxin system but not from glutaredoxin. May play an important role in eliminating peroxides generated during metabolism. Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H(2)O(2). Reduces an intramolecular disulfide bond in GDPD5 that gates the ability to GDPD5 to drive postmitotic motor neuron differentiation (By similarity).
About:
Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
Synonym names:
PAG; PAGA; PAGB; PRX1; PRXI; MSP23; NKEFA; TDPX2; NKEF-A; Peroxiredoxin-1; Natural killer cell-enhancing factor A; Proliferation-associated gene protein; Thioredoxin peroxidase 2; Thioredoxin-dependent peroxide reductase 2; PRDX1
Properties:
If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
Storage conditions:
Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
Source:
Sulfonylated peptide(KLH coupled) corresponding to the active site sequence common to mammalian Prx I to IV
Cross reactive species details:
Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
Specificity:
This is a highly specific antibody against Peroxiredoxin-SO3.
Also known as:
Peroxiredoxin-SO3 (10A1) Monoclonal Antibody
Long name:
Peroxiredoxin-SO3 (10A1) Monoclonal Antibody
Purification method:
Purified by Protein G.
Modification site(s):
Unmodified antibody
Category:
Primary Antibodies
Target Antigen:
Peroxiredoxin-SO3
Recommended dilutions:
WB (1.0 ug/mL)
Conjugation:
Unconjugated
Concentration:
1ug per 1ul
Clonality:
Monoclonal
French translation:
anticorps
Swiss Prot:
Q06830
Cross reactivity:
Human
Clone number:
10A1
Modification(s):
None
Gene ID number:
5052
Tested Applications:
WB