Properties:
If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.Biotin conjugates can be detected by horseradish peroxidase, alkaline phosphatase substrates or anti biotin conjugated antibodies. Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA. To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1.6.
Antigen background:
Involved in redox regulation of the cell. Reduces peroxides with reducing equivalents provided through the thioredoxin system. It is not able to receive electrons from glutaredoxin. May play an important role in eliminating peroxides generated during metabolism. Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H(2)O(2).
Synonyms:
PRP; TSA; PRX2; PTX1; TPX1; NKEFB; PRXII; TDPX1; NKEF-B; HEL-S-2a; Peroxiredoxin-2; Natural killer cell-enhancing factor B; Thiol-specific antioxidant protein; Thioredoxin peroxidase 1; Thioredoxin-dependent peroxide reductase 1; PRDX2
Specificity:
This is a highly specific antibody against Peroxiredoxin 2. This antibody may have a minor secondary cross-reactivity to related protein Peroxiredoxin 1 due to a 71% non-sequential sequence similarity over the immunogen range.
Storage conditions:
Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
Crossreactive species details:
Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
Source:
KLH conjugated synthetic peptide derived from human Peroxiredoxin 2
Long name:
Peroxiredoxin 2 Polyclonal Antibody, Biotin Conjugated
Purification method:
This antibody was purified via Protein A.
Recommended dilutions:
WB(1:100-1000), IHC-P(1:100-500)
Host Organism:
Rabbit (Oryctolagus cuniculus)
Category:
Conjugated Primary Antibodies
Clone:
Polyclonal antibody
Crossreactivity:
Human, Mouse, Rat
Target Antigen:
Peroxiredoxin 2
Additional conjugation:
Biotinylated
Immunogen_range:
150-197/198
Concentration:
1ug per 1ul
Clonality:
Polyclonal
Modification:
Unmodified
French translation:
anticorps
Tested applications:
WB, IHC-P
Subcellular location:
Cytoplasm
Swiss Prot:
P32119
Conjugation:
Biotin
Modification site:
None
Gene ID number:
7001
Excitation Emission:
N/A