FUNCTION: Enhances natural killer (NK) cells activity.CATALYTIC ACTIVITY: 2 R'-SH + ROOH = R'-S-S-R' + H2O + ROH.SUBUNIT: Homodimer; disulfide-linked, upon oxidation. May be found as a toroid-shaped decamer composed of 5 dimers, depending on pH and calcium concentration.SIMILARITY: Belongs to the ahpC/TSA family.SUBCELLULAR LOCATION: Cytoplasm.MISCELLANEOUS: The active site is the redox-active Cys-50 oxidized to Cys-SOH. Cys-SOH rapidly reacts with Cys-171-SH of the other subunit to form an intermolecular disulfide with a concomitant homodimer formation. The enzyme may be subsequently regenerated by reduction of the disulfide by thioredoxin.
PRDX2 antibody can be stored at 4 grades C for short term (weeks). Long term storage should be at -20 grades C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
NKEFB, TDPX1, Peroxiredoxin-2, Natural killer cell-enhancing factor B, NKEF-B, PRP, TSA, PRX2, PTX1, TPX1, NKEFB, PRXII, HEL-S-2a, Peroxiredoxin2, Thioredoxin peroxidase 1, Thioredoxin-dependent peroxide reductase 1, Thiol-specific antioxidant protein, NKEF
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
Peroxiredoxin-2 antibody can be used for the detection of Peroxiredoxin-2 by Western Blot.
Suspention, pH, azide:
Phosphate-Buffered Saline. No preservatives added.
21.8 kDa (calculated)
Human, Mouse, Rat
Vial with antibody:
Quantity per ml:
Ab raised in:
NCBI GENE nr: